. Diagnosis, treatment, and prevention of cancer .

We have begun placing the excellent tumor pathology JPEG images from
PC-Tumor BBS (407-234-1287) on our Laboratory Medicine/Pathology WWW
site <http://fester.his.path.cam.ac.uk/big/synapse/000p0025.htm>.  It is
a slow process as there are over 800 images. Thus far we are into the
B’s, twenty-four more letters of the alphabet to go!  I have listed
below the images there thus far.  We have not sharpened and color
corrected the images, so they are exactly as you would find them on the
BBS.  Many need no correction of any kind.  We plan eventually to offer
sharpened, color-corrected images for the ones requiring correction, but
if you want to try it yourself and have Photoshop, the correction on the
first image would be: red +36, sharpen (unsharp mask, 1.0 pixels) 72%.

You will find the access from the main page under Resources and the
designation "A variety of applications and resources that may be of
interest, including a selection of pathological images. Please Click
Here."  The direct URL for the subpage the images are on is
<http://fester.his.path.cam.ac.uk/big/synapse/000p031q.htm> but this
bypasses the access counter on the main page so we don’t get to know
about your visit!

Many thanks to John Minarcik sysop of PC-Tumor BBS (407-234-1287) for
providing these excellent images.

All the best. – Kim

PC-Tumor Images

Department of Laboratory Medicine & Pathology
University of Alberta

A:

Acid Fast Bacillus
       1. Acid Fast Bacillus stain of a granuloma found on a bronchial
biopsy of a cavitary lesion
       in a 30 year old Ft. Pierce woman. It’s positive. (41.6 kb)
11-11-93 (Courtesy of John
       Minarcik)

Acinic Carcinoma of Parotid Gland
       1. From CAP check sample. High power. Clear cytoplasm. Mitosis in
center (36.3 kb)
       08-06-93 (Courtesy of Peter Shireman)
       2. From CAP check sample. Low power. (53.8 kb) 08-06-93 (Courtesy
of Peter
       Shireman)

Actinic Keratosis
       1. Actinic Keratosis adjacent to a malignant melanoma. (40.8 kb)
04-13-93 (Courtesy of
       John Taz)

Acute Megakaryoblastic Leukemia
       1. Acute Megakaryoblastic Leukemia (Really!) (33.4 kb) 10-21-93
(Courtesy of John
       Minarcik)

Acute Myelogenous Leukemia
       1. Blast, from the peripheral blood smear. (19.0 kb) 11-22-92
(Courtesy of Peter
       Shireman)
       2. Bone Marrow. High Power. (26.8 kb) 12-03-92 (Courtesy of Peter
Shireman)
       3. Bone Marrow. Low Power. (28.9 kb) 12-03-92 (Courtesy of Peter
Shireman)
       4. Bone Marrow. Oil Immersion. Note total lack of differentiating
features. (23.7 kb)
       12-03-92 (Courtesy of Peter Shireman)
       5. Blast from the Bone Marrow. (22.0 kb) 11-02-92 (Courtesy of
Peter Shireman)

Acute Myelomonocytic Leukemia
       1. Acute myelomonocytic leukemia. (21.8 kb) 12-03-92 (Courtesy of
Peter Shireman)
       2. Acute myelomonocytie leukemia. Peripheral blood smear. (19.5
kb) 12-03-92
       (Courtesy of Peter Shireman)

Adenocarcinoma
       1. Found on duodenal biopsy. Primary? The search begins. (46.9
kb) 12-01-93 (Courtesy
       of John Minarcik)
       2. Metastatic poorly differentiated adenocarcinoma FROM lung to
liver. (42.3 kb)
       04-07-94 (Courtesy of John Minarcik)
       3. Metastatic poorly differentiated adenocarcinoma FROM colon to
omentum. (59.1 kb)
       04-07-94 (Courtesy of John Minarcik)

Adenocarcinoma of the Colon
       1. Note the loss of nuclear polarity, haphazard unorderly growth
pattern, and prominent
       nuclei and nucleoli. (41.6 kb) 10-01-92 (Courtesy of Taz)
       2. Note impingement of the glands up to and into smooth muscle.
(43.2 kb) 10-01-92
       (Courtesy of Taz)
       3. Note intiltration of tumour cells between smooth muscle
bundles, with secondary
       infiltration of inflammatory cells as well. (41.6 kb) 10-01-92
(Courtesy of Taz)
       4. Note metastasis of tumour cells into lymph node. (37.6 kb)
10-01-92 (Courtesy of Taz)
       5. Note the tumour cells within mucin lakes, or mucin pools.
(13.3 kb) 05-10-93
       (Courtesy of Peter Shireman)
       6. Note sclerosis. (29.8 kb) 05-10-93 (Courtesy of Peter
Shireman)
       7. Note abortive or primitive gland (acinar) formation. (26.1 kb)
05-10-93 (Courtesy of
       Peter Shireman)
       8. Low power. (23.3 kb) 05-10-93 (Courtesy of Peter Shireman)
       9. PAS stain. (33.7 kb) 05-10-93 (Courtesy of Peter Shireman)
       10. (Periodic Acid Schiff) stain. (32.4 kb) 05-10-93 (Courtesy of
Peter Shireman)
       11. (Periodic Acid Schiff) stain. (29.8 kb) 05-10-93 (Courtesy of
Peter Shireman)
       12. PAS stain. Medium power. (59.3 kb) 08-06-93 (Courtesy of
Peter Shireman)
       13. PAS stain. High power. Note tumour Giant Cells. (48.0 kb)
08-06-93 (Courtesy of
       Peter Shireman)
       14. Ileocecal valve. Gross photograph. (34.4 kb) 01-17-94
(Courtesy of Peter Shireman)
       15. Invading pericolonic fat. Gross photograph. (35.2 kb)
01-17-94 (Courtesy of Peter
       Shireman)
       16. Cut surface, invading into fat. Gross photograph. (26.6 kb)
01-17-94 (Courtesy of
       Peter Shireman)
       17. Fresh, raised and ulcerated tumour. Gross photograph. (65.3
kb) 01-17-94 (Courtesy
       of Peter Shireman)
       18. Cut surface, invading into fat. Gross photograph. (46.7 kb)
01-17-94 (Courtesy of
       Peter Shireman)
       19. Ascitic fluid in a man with disseminated colon
adenocarcinoma. (36.3 kb) 04-06-94
       (Courtesy of John Minarcik)
       20. Poorly differentiated adenocarcinoma of colon, sigmoid,
showing signet ring cells.
       (44.5 kb) 07-18-93

B:

Basal Cell Carcinoma
       1. Note large spindly, occasionally nucleolated, nuclei. (40.8
kb) 10-08-92 (Courtesy of
       John Minarcik)

Blastomycosis
       1. Blastomycosis in bronchial washings. (40.2 kb) 11-22-93
(Courtesy of Mariano Alvira)
       2. Composite. Bronchial washings. (42.2 kb) 11-22-93 (Courtesy of
Mariano Alvira)

Bowenoid Actinic Keratosis
       1. Bowenoid actinic keratosis in skin of forehead of 79 year old
Florida woman. (34.9 kb)
       09-24-93 (Courtesy of John Minarcik)

Brain Hemorrhage
       1. Traumatic brain hemorrhage. Gross photo. (24.5 kb) 11-22-93
(Courtesy of Mariano
       Alvira)

Breast
       1. Benign calcifications seen microscopically. Breast frozen
section. (37.0 kb) 01-15-93
       (Courtesy of Taz)
       2. Intraductal and infiltrating ductal of breast. Low power.
(44.3 kb) 07-28-93 (Courtesy
       of Peter Shireman)
       3. Intraductal and infiltrating ductal of breast. High power.
(42.4 kb) 07-28-93 (Courtesy
       of Peter Shireman)
       4. Infiltrating ductal carcinom of breast. High power. (54.3 kb)
07-28-93 (Courtesy of
       Peter Shireman)
       5. Infiltrating ductal carcinoma of breast. High power. (50.4 kb)
07-28-93 (Courtesy of
       Peter Shireman)
       6. Calcifications, intraductal, associated with breast carcinoma.
(53.9 kb) 11-05-93
       (Courtesy of Quincy)

Breast Carcinoma
       1. A nest of breast carcinoma cells within a lymphatic vessel.
(34.9 kb) 04-08-93
       (Courtesy of Rudy Virchow)
       2. Classical ductal carcinoma of breast. High power. (47.1 kb)
11-05-93 (Courtesy of Bill
       Supan)
       3. High power. (50.3 kb) 11-09-93 (Courtesy of Gary Marder)

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