. Diagnosis, treatment, and prevention of cancer .

Please don’t forget hydrazine sulfate, PLEASE!

I apologize to all of you that couldn’t reach me with my first request.  
Please try again using this temporary e-mail address:  
mgru…@vmarketing.com

I am writing for my second time requesting any help available for the
success rates of sibling bone marrow transplants.  My father-in-law (53
years old) is weighing his options, and I welcome any info you can
offer.

Thanks for your help.

Is  maltoma lymphoma a new subgroup of lymphoma. Where does it fit into the old
classification? Is there any other information about prognosis and treatment?

I read in a Malaysian Chinese newspaper that two terminal cases of the
cancer of the liver were cured by Russian doctors in the Central Research
Institute of Roentgenology, Radiology and Oncology, St Petersburg,
Russia. The treatment appears to be in the form of intrahepatic infusion
of some drugs.  A friend of mine is thinking of seeking treatment there.

Does anyone have more specific information about the work in that
institute.  What drugs are used?  Is it cytotoxic , radionuclide or some
other stuff ?

Thanks.

Jonathan Corbet (cor…@stout.atd.ucar.edu) wrote:

: My wife was found to have a stage-II ductal breast cancer, with one node
: involved.  We’re a couple of months into this ride now, with the second
: adriamycin blast coming up.  But she is finding herself questioning the
: value of the chemotherapy ever more.  From what she has read, she has
: reached the following conclusion:

:       Adjuvant chemotherapy can never do more than delay a recurrance in
:       breast cancer.  Just as many women are dying from the disease now
:       as were before the use of adjuvant chemo, only it happens a little
:       later.

: So…my question is: is there anybody out there who can point to some
: definitive results about the long-term value of adjuvant chemotherapy?  Any
: information would be much appreciated.

        Fortunately, your wife is wrong.  There is abundant evidence of
the long term benefit of chemotherapy for stage II breast cancer.  Here is
a citation of a recently published study with 20 year follow-up.  [N.B.
The chemotherapy used in this study was used in attentuated doses in
post-menopausal women, and that probably accounts for the fact that the
benefit seen was only in pre-menopausal women.  Subsequent studies show
that chemotherapy in full doses can also benefit other women.]

Unique Identifier
  95183090
Authors
  Bonadonna G.  Valagussa P.  Moliterni A.  Zambetti M.  Brambilla C.
Institution
  Division of Medical Oncology, Istituto Nazionale Tumori, Milan, Italy.
Title
  Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive
  breast cancer: the results of 20 years of follow-up [see comments].
Source
  New England Journal of Medicine.  332(14):901-6, 1995 Apr 6.
Abstract
  BACKGROUND. Adjuvant combination chemotherapy with cyclophosphamide,
  methotrexate, and fluorouracil was administered after radical mastectomy
  for primary breast cancer with histologically positive axillary lymph nodes
  to assess whether it would improve treatment outcome as compared with
  surgery alone. Here we report a 20-year follow-up of this investigation.
  METHODS. In 1973 we began a trial involving 386 women who were randomly
  assigned to receive either no further treatment after radical mastectomy
  (179 women) or 12 monthly cycles of adjuvant combination chemotherapy (207
  women). All patients were admitted to the Istituto Nazionale Tumori in
  Milan, Italy. Adjuvant chemotherapy was delivered in the outpatient clinic
  of the Division of Medical Oncology. RESULTS. After a median follow-up of
  19.4 years, the patients given adjuvant combination chemotherapy had
  significantly better rates of relapse-free survival (unadjusted relative
  risk of relapse, 0.71; 95 percent confidence interval, 0.56 to 0.90; P =
  0.004; adjusted relative risk, 0.65, 95 percent confidence interval, 0.51
  to 0.83; P < 0.001) and total survival (unadjusted relative risk of death,
  0.78; 95 percent confidence interval, 0.62 to 0.99; P = 0.04; adjusted
  relative risk, 0.76; 95 percent confidence interval, 0.60 to 0.97; P =
  0.03). With the exception of postmenopausal women, a benefit from adjuvant
  chemotherapy was evident in all subgroups of patients. CONCLUSIONS. The
  long-term results of this trial of adjuvant combination chemotherapy
  confirm our preliminary observations of the effectiveness of the treatment
  in women with node-positive breast cancer.

        Best wishes,
        Eric Chevlen, MD

Do you have or know of any one who has Waldenstrom’s Macroglobulinemia?

There is a WM Support Group and telephone network for this rare cancer
condition. This group publishes an information newsletter. There are no
dues or fees to join. WM patients, friends, relatives, etc. from any
country are sent copies of the newsletter.

For more information and to receive a set of back issues (8 to date) of
the newsletter leave me a messge with your mailing address. The
newsletters are not available elextronically only hard copy at this time.

Arnold Smokler
7917 Hatteras Lane
Springfield, VA 22151-2410
USA
Phone: 703-321-8888
FAX:     703-321-8920
BBS:    703-321-8070
Internet ID: dpmc…@prodigy.com
Prodigy ID: DPMC11A

Dr.Marcus Niewald (ram…@med-rz.uni-sb.de) wrote:

: Does anyone know national or international criteria regarding good
: manufacturing practice in radiation of blood or plasma products in order to
: avoid graft-versus-host-reactions?

: Are there criteria concerning dosimetry and inhomogeneity of dose
: distributions?

: Please reply to ram…@med-rz.uni-sb.de (Dr.M.Niewald)
Have you tried the Association of American Blood Banks guide?

Please feel free to drop by and take a look-see at the new "Chronic
Disease & Disorders Forum" (from the Fitness & Health Forum go to
"Public Health"), on the Microsoft Network. There is a BBS devoted
exclusively to those who have or have had cancer, their families,
friends, caregivers and the medical community.

"The Big ‘C’ BBS" provides a warm and supportive place where you’ll
meet others who are living similar life experiences as yourself.

Lookin’ forward to seeing ya on MSN…

Barbara Mallut
Forum Manager,
Chronic Disease & Disorders Forum
The Microsoft Network

A relative of mine has a swelling in her right wrist. This has been
diagnosed as CELLULITIS. I am worried that this may be a form of cancer.
Is it?

– Visa